If it seems that your toes are getting crowded in your shoes, there are a couple things that may be happening. First, you may have the wrong size or style of shoe.
Some newer styles of shoes have a tight or pointy toe box and this can cause the toes to be close together and there may actually be irritation of the skin on adjacent toes. Another common cause for toes to get close together is bunions. This deformity of the big toe joint causes leaning of the big toe into the others (especially the second toe). This can cause irritation between toes as well as on the inside aspect of the big toe joint.