Pain from a neuroma is caused by an enlarged, inflamed nerve that runs between the long bones of the foot and along the toes, most commonly the 3rd and 4th digits, although it can occur between any toes.  Since this nerve is an inflammation, some anti inflammatory medications may help the symptoms.  OTC (over-the counter) anti inflammatory medications that are not steroids are referred to NSAIDs, or non steroidal anti inflammatories.  Examples of NSAIDs include Motrin, ibuprofin, or Aleve.  There are also prescription anti inflammatory medications, such as Mobic (Meloxicam) or Naprosyn (Naproxen sodium.) Although you may get temporary relief from these medications, it is important to address the cause of the pain and not just treat the symptoms.  By making an appointment with one of our doctors, we can help you treat the neuroma itself, not just the pain.